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KMID : 0360419660020010041
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Korean Journal of Pharmacology
1966 Volume.2 No. 1 p.41 ~ p.48
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Studies on the adrenotropic receptors of the uteri of the rabbit and rat
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Abstract
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The author studied the adrenotropic receptors of the non-pregnant uteri of the rabbit and rat, using epinephrine (alpha and beta activator), phenoxybenzamine(alpha blocking agent) and nethalide (beta blockade), and obtained the following results:
1. The spontaneous motility of isolated non-pregnant uteri from rabbits were stimulated by epinephrine, whereas that of isolated non-pregnant rat uterus was inhibited by epinephrine.
2. Both alpha and beta adrenergic receptors were present in the uterine muscle of both animals.
3. In the non-pregnant rabbit uterus, alpha receptors were predominant, whereas in the non -pregnant rat uterus, beta receptors preponderated over alpha receptors.
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